where to find micronutrient therapy in Villanova?

oxidative balance score during pregnancy is associated with oxidative stress in the candle study

author(s): tylavsky, frances a; han, luhang; taylor, lauren m sims; mason, w alex; carroll, kecia n; bush, nicole r; lewinn, kaja z; melough, melissa m; hartman, terryl j; zhao, qi | abstract: the objective of this study was to calculate an oxidative balance score (obs) utilizing diet and lifestyle information collected from 1322 women during the second trimester of pregnancy in the conditions affecting neurocognitive development and learning in early childhood study. an energy-adjusted obs was calculated using nutrient information from a food frequency questionnaire (ffq), lifestyle measures, and plasma folate and vitamin d levels. using the least absolute shrinkage and selection operator method, 91 food items from the ffq were selected and they accounted for 82% of the variance in the obs, with cruciferous vegetables, citrus fruits, fruit juice, and coffee being among the highest anti-oxidant predictors, and red meats and alcohol among the highest pro-oxidant contributors. urinary f2-isoprostane, an objective indicator of oxidative stress, was lower with increasing obs quintiles in a stairstep manner (p for trend = 0.0003), suggesting the possible utility of the obs as an indicator of oxidative stress. the obs was moderately correlated with the healthy eating index (correlation coefficient = 0.6076), suggesting it provides a distinct measure of a healthy diet. in conclusion, the obs may serve as a valid reflective indicator of urinary f2-isoprostanes and an epidemiological tool to inform intervention studies, in order to minimize oxidative stress during pregnancy.

dietetic intern research articles | human sciences | sfa

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pharmacological agents for the prevention of colistin-induced nephrotoxicity - european journal of medical research

background colistin is a polymyxin antibiotic which has been used for treatment of gram-negative infections, but it was withdrawn due to its nephrotoxicity. however, colistin has gained its popularity in recent years due to the reemergence of multidrug resistant gram-negative infections and drug-induced toxicity is considered as the main obstacle for using this valuable antibiotic. results in total, 30 articles, including 29 animal studies and one clinical trial were included in this study. these compounds, including aged black garlic extract, albumin fragments, alpha lipoic acid, astaxanthin, baicalein, chrysin, cilastatin, colchicine, curcumin, cytochrome c, dexmedetomidine, gelofusine, grape seed proanthocyanidin extract, hesperidin, luteolin, lycopene, melatonin, methionine, n-acetylcysteine, silymarin, taurine, vitamin c, and vitamin e exhibited beneficial effects in most of the published works. conclusions in this review, the authors have attempted to review the available literature on the use of several compounds for prevention or attenuation of colistin-induced nephrotoxicity. most of the studied compounds were potent antioxidants, and it seems that using antioxidants concomitantly can have a protective effect during the colistin exposure.

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biomedicine - zabrecky institute of biomedicine | integrative and functional medicine | philadelphia & villanova

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work with me — nate handley md

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virtual posters | society for biomaterials (sfb)

  bioglasses/ceramics/other hard materials v1. adsorption behavior of serum proteins on the surface of hydroxyapatite ceramics with preferred orientation to a-plane, erika onuma, graduate school of science and technology, meiji university, onuma@meiji.ac.jp

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review of natural compounds for potential psoriasis treatment - inflammopharmacology

psoriasis represents an immune-mediated disease with an unclear cause that’s marked by inflammation triggered by dysfunction in the immune system, which results in inflammation in various parts of the skin. there could be obvious symptoms, such as elevated plaques; these plaques may appear differently depending on the type of skin. this disease can cause inflammation in the elbows, lower back, scalp, knees, or other regions of the body. it can begin at any age, although it most commonly affects individuals between the ages of 50 and 60. specific cells (such as t cells) have been observed to play an obvious role in the pathogenesis of psoriasis, in addition to specific immunological molecules such as tnf-, il-12, il-23, il-17, and other molecules that can aid in the pathogenesis of psoriasis. so, during the past two decades, biologists have created chemical drugs that target these cells or molecules and therefore prevent the disease from occurring. alefacept, efalizumab, adalimumab, ustekinumab, and secukinumab are a few examples of chemical drugs. it was discovered that these chemical drugs have long-term side effects that can cause defects in the patient's body, such as the development of the rare but life-threatening disorder progressive multifocal leukoencephalopathy (pcl). its rapidly progressive infection of the central nervous system caused by the jc virus and other drugs may cause increased production of neutralising anti-drug antibodies (ada) and the risk of infusion reactions like pruritus, flushing, hypertension, headache, and rash. so, our context intends to talk in our review about natural products or plants that may have therapeutic characteristics for this disease and may have few or no side effects on the patient's body.

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